Both mps(4) and mpr(4) drivers were found to report CAM bigger queue depth then they really can handle. It makes them later under high load with many disks return some of submitted requests back with CAM_REQUEUE_REQ status for later resubmission (can be seen with CAM error logging enabled with camcontrol debug -I all).
It may both reduce performance and potentially affect some third-party software trying to talks disks directly with SCSI commands.