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diff --git a/biology/hyphy/Makefile b/biology/hyphy/Makefile
--- a/biology/hyphy/Makefile
+++ b/biology/hyphy/Makefile
@@ -1,5 +1,6 @@
PORTNAME= hyphy
DISTVERSION= 2.5.77
+PORTREVISION= 1
CATEGORIES= biology
MAINTAINER= jrm@FreeBSD.org
@@ -20,9 +21,11 @@
USE_GITHUB= yes
GH_ACCOUNT= veg
-OPTIONS_DEFINE= AVX
-AVX_DESC= Advanced vector extensions support
+OPTIONS_DEFINE= AVX TARGET_NATIVE
+AVX_DESC= Advanced vector extensions support
+TARGET_NATIVE_DESC= Enable CPU-specific instructions and tuning for build machine
-AVX_CMAKE_BOOL_OFF= NOAVX
+AVX_CMAKE_BOOL_OFF= NOAVX
+TARGET_NATIVE_CMAKE_BOOL= TARGET_NATIVE
.include <bsd.port.mk>

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