Originally pypy did not build on FreeBSD due to build failure in rvmprof. In order to build it on FreeBSD (and OpenBSD) you had to disable rvmprof during build process. This is what the previous patch (D16138) was doing to enable build on FreeBSD.
Now I obtained a patch from upstream [1] that actually solves the rvmprof build problem and you can now have pypy/pypy3 on FreeBSD with rvmprof enabled.
[1] (https://bitbucket.org/pypy/pypy/issues/2853/build-fails-on-freebsd-11x-x64#comment-46813575)