Index: head/biology/py-scikit-bio/Makefile
===================================================================
--- head/biology/py-scikit-bio/Makefile	(revision 549973)
+++ head/biology/py-scikit-bio/Makefile	(revision 549974)
@@ -1,31 +1,38 @@
 # $FreeBSD$
 
 PORTNAME=	scikit-bio
 PORTVERSION=	0.5.6
 CATEGORIES=	biology python
 MASTER_SITES=	CHEESESHOP
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Data structures, algorithms, educational resources for bioinformatics
 
 LICENSE=	BSD3CLAUSE
 LICENSE_FILE=	${WRKSRC}/COPYING.txt
 
 BUILD_DEPENDS=	${PYNUMPY}
 RUN_DEPENDS=	${PYNUMPY} \
 		${PYTHON_PKGNAMEPREFIX}CacheControl>=0.11.5:www/py-cachecontrol@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}decorator>=3.4.2:devel/py-decorator@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}hdmedians>=0.13:math/py-hdmedians@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}ipython>=3.2.0:devel/ipython@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}lockfile>=0.10.2:devel/py-lockfile@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}matplotlib>=1.4.3:math/py-matplotlib@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}natsort>=4.0.3:devel/py-natsort@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pandas>=1.0.0:math/py-pandas@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}scikit-learn>=0.19.1:science/py-scikit-learn@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}scipy>0:science/py-scipy@${PY_FLAVOR}
 
 USES=		python:3.7+
 USE_PYTHON=	autoplist distutils
 
-.include <bsd.port.mk>
+.include <bsd.port.pre.mk>
+
+.if ${ARCH} == i386
+CFLAGS+=	-msse2 # workaround for https://github.com/biocore/scikit-bio/issues/1727
+CXXFLAGS+=	-msse2
+.endif
+
+.include <bsd.port.post.mk>