Index: head/biology/py-macs2/Makefile
===================================================================
--- head/biology/py-macs2/Makefile	(revision 522686)
+++ head/biology/py-macs2/Makefile	(revision 522687)
@@ -1,32 +1,29 @@
 # $FreeBSD$
 
-PORTNAME=	macs2
-PORTVERSION=	2.1.0.p20170505
-PORTREVISION=	3
-CATEGORIES=	biology python
-PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
+PORTNAME=		macs2
+DISTVERSIONPREFIX=	v
+DISTVERSION=		2.2.6
+CATEGORIES=		biology python
+PKGNAMEPREFIX=		${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	jwb@FreeBSD.org
-COMMENT=	Analysis of chromatin immunoprecipitation (ChIP) sequences
+COMMENT=	Identify transcription factor binding sites
 
 LICENSE=	BSD3CLAUSE
-LICENSE_FILE=	${WRKSRC}/COPYING
+LICENSE_FILE=	${WRKSRC}/LICENSE
 
 BUILD_DEPENDS=	${PYNUMPY}
 
-USES=		python:2.7
+USES=		python:3.6+
 USE_PYTHON=	autoplist concurrent cython distutils
 
 USE_GITHUB=	yes
 GH_ACCOUNT=	taoliu
 GH_PROJECT=	MACS
-GH_TAGNAME=	6946b2f
-
-PYSETUP=	setup_w_cython.py
 
 post-stage:
 	${STRIP_CMD} \
 		${STAGEDIR}${PYTHON_SITELIBDIR}/MACS2/*.so \
 		${STAGEDIR}${PYTHON_SITELIBDIR}/MACS2/*/*.so
 
 .include <bsd.port.mk>
Index: head/biology/py-macs2/distinfo
===================================================================
--- head/biology/py-macs2/distinfo	(revision 522686)
+++ head/biology/py-macs2/distinfo	(revision 522687)
@@ -1,3 +1,3 @@
-TIMESTAMP = 1512241922
-SHA256 (taoliu-MACS-2.1.0.p20170505-6946b2f_GH0.tar.gz) = c6e4fb8b69b955134399fcdfc075cea5fbc29fabbc46cc4e9acdedeb1174fcfd
-SIZE (taoliu-MACS-2.1.0.p20170505-6946b2f_GH0.tar.gz) = 159560613
+TIMESTAMP = 1578626999
+SHA256 (taoliu-MACS-v2.2.6_GH0.tar.gz) = 7c51561787d15d85370b11c9121e4ab7174ce11cfde36043b9ee95de8451db3a
+SIZE (taoliu-MACS-v2.2.6_GH0.tar.gz) = 133721230

Property changes on: head/biology/py-macs2/distinfo
___________________________________________________________________
Modified: fbsd:nokeywords
## -1 +1 ##
-on
\ No newline at end of property
+yes
\ No newline at end of property