diff --git a/science/orthanc-mysql/Makefile b/science/orthanc-mysql/Makefile
index 37620e7c7b54..7365fb5e0cc3 100644
--- a/science/orthanc-mysql/Makefile
+++ b/science/orthanc-mysql/Makefile
@@ -1,51 +1,52 @@
 PORTNAME=	orthanc-mysql
 DISTVERSION=	5.2
+PORTREVISION=	1
 CATEGORIES=	science
 MASTER_SITES=	https://orthanc.uclouvain.be/downloads/sources/orthanc-mysql/:mysql \
 		https://orthanc.uclouvain.be/downloads/sources/orthanc/:orthanc \
 		https://orthanc.uclouvain.be/downloads/third-party-downloads/:thirdparty
 DISTFILES=	OrthancMySQL-${PORTVERSION}.tar.gz:mysql \
 		Orthanc-${ORTHANC_VER}.tar.gz:orthanc \
 		e2fsprogs-1.44.5.tar.gz:thirdparty
 DIST_SUBDIR=	orthanc
 EXTRACT_ONLY=	OrthancMySQL-${PORTVERSION}.tar.gz
 
 MAINTAINER=	jwb@FreeBSD.org
 COMMENT=	Orthanc plugin to use MySQL/MariaDB for indexing or storage
 WWW=		https://www.orthanc-server.com/static.php?page=mysql
 
 LICENSE=	AGPLv3
 LICENSE_FILE=	${WRKSRC}/COPYING
 
 BUILD_DEPENDS=	${LOCALBASE}/include/orthanc/OrthancCDatabasePlugin.h:science/orthanc \
 		googletest>0:devel/googletest
 LIB_DEPENDS=	libboost_filesystem.so:devel/boost-libs \
 		libcurl.so:ftp/curl \
 		libjsoncpp.so:devel/jsoncpp \
 		libprotobuf.so:devel/protobuf
 RUN_DEPENDS=	Orthanc:science/orthanc
 
 USES=		cmake localbase mysql:client python:build ssl
 USE_LDCONFIG=	${DATADIR}/plugins
 
 WRKSRC=		${WRKDIR}/OrthancMySQL-${PORTVERSION}
 
 CMAKE_ARGS=	-DORTHANC_FRAMEWORK_ROOT=${WRKSRC}/MySQL/ThirdPartyDownloads/Orthanc-${ORTHANC_VER}/OrthancFramework/Sources \
 		-DORTHANC_FRAMEWORK_SOURCE=path
 CMAKE_OFF=	DBUILD_UNIT_TESTS USE_SYSTEM_ORTHANC_SDK USE_SYSTEM_UUID
 CMAKE_SOURCE_PATH=	${WRKSRC}/MySQL
 
 CFLAGS+=	-DORTHANC_ENABLE_LOGGING_PLUGIN -DNDEBUG
 CXXFLAGS+=	-I${LOCALBASE}/include -DNDEBUG
 
 PLIST_SUB=	DISTVERSION=${DISTVERSION}
 
-ORTHANC_VER=	1.12.9
+.include "${.CURDIR}/../../science/orthanc/version.mk"
 
 post-extract:
 		${MKDIR} ${WRKSRC}/MySQL/ThirdPartyDownloads
 		${CP} ${DISTDIR}/${DIST_SUBDIR}/e2fsprogs-1.44.5.tar.gz ${WRKSRC}/MySQL/ThirdPartyDownloads
 		${CP} ${DISTDIR}/${DIST_SUBDIR}/Orthanc-${ORTHANC_VER}.tar.gz ${WRKSRC}/MySQL/ThirdPartyDownloads
 		${TAR} -C ${WRKSRC}/MySQL/ThirdPartyDownloads -xf ${WRKSRC}/MySQL/ThirdPartyDownloads/Orthanc-${ORTHANC_VER}.tar.gz
 
 .include <bsd.port.mk>
diff --git a/science/orthanc-mysql/distinfo b/science/orthanc-mysql/distinfo
index 7b57fb02015e..facf4c2a58d5 100644
--- a/science/orthanc-mysql/distinfo
+++ b/science/orthanc-mysql/distinfo
@@ -1,7 +1,7 @@
-TIMESTAMP = 1761521650
+TIMESTAMP = 1764253462
 SHA256 (orthanc/OrthancMySQL-5.2.tar.gz) = 0d446b53c3fdaa66d9f2365864f1ac54d133fe3760d7d3bb52c850ca67ce9fbb
 SIZE (orthanc/OrthancMySQL-5.2.tar.gz) = 603876
-SHA256 (orthanc/Orthanc-1.12.9.tar.gz) = 7a7cbc5f3663939fbef31ded021b36fcd52420337911ed43491bb663bcb5a4b2
-SIZE (orthanc/Orthanc-1.12.9.tar.gz) = 2165182
+SHA256 (orthanc/Orthanc-1.12.10.tar.gz) = b5d6934d123182fb2186cd54ef7f203be06b544afb03df67b0c64ad68d6c9286
+SIZE (orthanc/Orthanc-1.12.10.tar.gz) = 2192892
 SHA256 (orthanc/e2fsprogs-1.44.5.tar.gz) = 2e211fae27ef74d5af4a4e40b10b8df7f87c655933bd171aab4889bfc4e6d1cc
 SIZE (orthanc/e2fsprogs-1.44.5.tar.gz) = 7619237
diff --git a/science/orthanc-mysql/files/patch-OrthancFramework_Resources_CMake_ProtobufConfiguration.cmake b/science/orthanc-mysql/files/patch-OrthancFramework_Resources_CMake_ProtobufConfiguration.cmake
index e4826a677166..24de235a27d8 100644
--- a/science/orthanc-mysql/files/patch-OrthancFramework_Resources_CMake_ProtobufConfiguration.cmake
+++ b/science/orthanc-mysql/files/patch-OrthancFramework_Resources_CMake_ProtobufConfiguration.cmake
@@ -1,47 +1,47 @@
---- MySQL/ThirdPartyDownloads/Orthanc-1.12.9/OrthancFramework/Resources/CMake/ProtobufConfiguration.cmake.orig	2025-08-11 16:02:50 UTC
-+++ MySQL/ThirdPartyDownloads/Orthanc-1.12.9/OrthancFramework/Resources/CMake/ProtobufConfiguration.cmake
+--- MySQL/ThirdPartyDownloads/Orthanc-1.12.10/OrthancFramework/Resources/CMake/ProtobufConfiguration.cmake.orig	2025-08-11 16:02:50 UTC
++++ MySQL/ThirdPartyDownloads/Orthanc-1.12.10/OrthancFramework/Resources/CMake/ProtobufConfiguration.cmake
 @@ -60,27 +60,31 @@ else()
      add_custom_target(ProtobufCompiler)
    endif()
    
 -  check_include_file_cxx(google/protobuf/any.h HAVE_PROTOBUF_H)
 -  if (NOT HAVE_PROTOBUF_H)
 -    message(FATAL_ERROR "Please install the libprotobuf-dev package")
 -  endif()
 +  if (${CMAKE_SYSTEM_NAME} STREQUAL "FreeBSD")
 +    find_package(Protobuf REQUIRED)
 +  else()
 +    check_include_file_cxx(google/protobuf/any.h HAVE_PROTOBUF_H)
 +    if (NOT HAVE_PROTOBUF_H)
 +      message(FATAL_ERROR "Please install the libprotobuf-dev package")
 +    endif()
  
 -  set(CMAKE_REQUIRED_LIBRARIES "protobuf")
 +    set(CMAKE_REQUIRED_LIBRARIES "protobuf")
  
 -  include(CheckCXXSourceCompiles) 
 -  check_cxx_source_compiles(
 -    "
 +    include(CheckCXXSourceCompiles) 
 +    check_cxx_source_compiles(
 +      "
  #include <google/protobuf/descriptor.h>
  int main()
  {
    google::protobuf::FieldDescriptor::TypeName(google::protobuf::FieldDescriptor::TYPE_FLOAT);
  }
 -"  HAVE_PROTOBUF_LIB)
 -  if (NOT HAVE_PROTOBUF_LIB)
 -    message(FATAL_ERROR "Cannot find the protobuf library")
 -  endif()
 +  "  HAVE_PROTOBUF_LIB)
 +    if (NOT HAVE_PROTOBUF_LIB)
 +      message(FATAL_ERROR "Cannot find the protobuf library")
 +    endif()
    
 -  unset(CMAKE_REQUIRED_LIBRARIES)
 +    unset(CMAKE_REQUIRED_LIBRARIES)
 +  endif()
  
    link_libraries(protobuf)
  endif()