diff --git a/emulators/virtualbox-ose-legacy/Makefile b/emulators/virtualbox-ose-legacy/Makefile
--- a/emulators/virtualbox-ose-legacy/Makefile
+++ b/emulators/virtualbox-ose-legacy/Makefile
@@ -323,8 +323,8 @@
 	    ${WRKSRC}/src/VBox/Runtime/Makefile.kmk
 	@${ECHO_CMD} 'VBOX_ICONV_DEFS = LIBICONV_PLUG' >> ${WRKSRC}/LocalConfig.kmk
 .endif
-	@${REINPLACE_CMD} -e 's|/usr/local/lib/virtualbox|${VBOX_DIR}|' \
-	    -e 's|/usr/local|${PREFIX}|' \
+	@${REINPLACE_CMD} -e 's|%%VBOX_DIR%%|${VBOX_DIR}|g' \
+	    -e 's|%%LOCALBASE%%|${PREFIX}|g' \
 	    ${WRKSRC}/src/VBox/Installer/freebsd/VBox.sh
 	@${REINPLACE_CMD} \
 	    -e 's|^versions =.*|versions = ["${PYTHON_VER}${PYTHON_ABIVER}"]|' \
diff --git a/emulators/virtualbox-ose-legacy/files/patch-src-VBox-Installer-freebsd-VBox.sh b/emulators/virtualbox-ose-legacy/files/patch-src-VBox-Installer-freebsd-VBox.sh
--- a/emulators/virtualbox-ose-legacy/files/patch-src-VBox-Installer-freebsd-VBox.sh
+++ b/emulators/virtualbox-ose-legacy/files/patch-src-VBox-Installer-freebsd-VBox.sh
@@ -16,15 +16,15 @@
 +# hope that it will be useful, but WITHOUT ANY WARRANTY of any kind.
 +#
 +
-+PATH="/usr/bin:/bin:/usr/sbin:/sbin"
-+CONFIG="/usr/local/etc/vbox/vbox.cfg"
++PATH="/sbin:/bin:/usr/sbin:/usr/bin:%%LOCALBASE%%/sbin:%%LOCALBASE%%/bin"
++CONFIG="%%LOCALBASE%%/etc/vbox/vbox.cfg"
 +
 +test -r "${CONFIG}" &&
 +    . "${CONFIG}"
 +test -z "${INSTALL_DIR}" &&
-+    if test -d /usr/local/lib/virtualbox &&
-+        test -f /usr/local/lib/virtualbox/VBoxRT.so; then
-+        INSTALL_DIR=/usr/local/lib/virtualbox
++    if test -d %%VBOX_DIR%% &&
++        test -f %%VBOX_DIR%%/VBoxRT.so; then
++        INSTALL_DIR=%%VBOX_DIR%%
 +    else
 +        echo "Could not find VirtualBox installation. Please reinstall."
 +        exit 1
diff --git a/emulators/virtualbox-ose/Makefile b/emulators/virtualbox-ose/Makefile
--- a/emulators/virtualbox-ose/Makefile
+++ b/emulators/virtualbox-ose/Makefile
@@ -325,10 +325,11 @@
 	    ${WRKSRC}/src/VBox/Runtime/Makefile.kmk
 	@${ECHO_CMD} 'VBOX_ICONV_DEFS = LIBICONV_PLUG' >> ${WRKSRC}/LocalConfig.kmk
 .endif
-	# Causes a "reinplace" QA warning with default PREFIX/VBOX_DIR
-	@${REINPLACE_CMD} -e 's|/usr/local/lib/virtualbox|${VBOX_DIR}|' \
-	    -e 's|/usr/local|${PREFIX}|' \
+	@${REINPLACE_CMD} -e 's|%%VBOX_DIR%%|${VBOX_DIR}|g' \
+	    -e 's|%%LOCALBASE%%|${PREFIX}|g' \
 	    ${WRKSRC}/src/VBox/Installer/freebsd/VBox.sh
+        @${REINPLACE_CMD} -e 's|%%LOCALBASE%%|${PREFIX}|g' \
+	    ${WRKSRC}/src/VBox/HostDrivers/adpctl/VBoxNetAdpCtl.cpp
 	@${REINPLACE_CMD} \
 	    -e 's|^versions =.*|versions = ["${PYTHON_VER}${PYTHON_ABIVER}"]|' \
 	    ${WRKSRC}/src/libs/xpcom18a4/python/gen_python_deps.py
diff --git a/emulators/virtualbox-ose/files/patch-src-VBox-Installer-freebsd-VBox.sh b/emulators/virtualbox-ose/files/patch-src-VBox-Installer-freebsd-VBox.sh
--- a/emulators/virtualbox-ose/files/patch-src-VBox-Installer-freebsd-VBox.sh
+++ b/emulators/virtualbox-ose/files/patch-src-VBox-Installer-freebsd-VBox.sh
@@ -16,15 +16,15 @@
 +# hope that it will be useful, but WITHOUT ANY WARRANTY of any kind.
 +#
 +
-+PATH="/usr/bin:/bin:/usr/sbin:/sbin"
-+CONFIG="/usr/local/etc/vbox/vbox.cfg"
++PATH="/sbin:/bin:/usr/sbin:/usr/bin:%%LOCALBASE%%/sbin:%%LOCALBASE%%/bin"
++CONFIG="%%LOCALBASE%%/etc/vbox/vbox.cfg"
 +
 +test -r "${CONFIG}" &&
 +    . "${CONFIG}"
 +test -z "${INSTALL_DIR}" &&
-+    if test -d /usr/local/lib/virtualbox &&
-+        test -f /usr/local/lib/virtualbox/VBoxRT.so; then
-+        INSTALL_DIR=/usr/local/lib/virtualbox
++    if test -d %%VBOX_DIR%% &&
++        test -f %%VBOX_DIR%%/VBoxRT.so; then
++        INSTALL_DIR=%%VBOX_DIR%%
 +    else
 +        >&2 echo "Could not find VirtualBox installation. Please reinstall."
 +        exit 1
@@ -33,7 +33,7 @@
 +if [ -d /etc/vbox ]; then
 +    >&2 cat <<-EOH
 +	WARNING: Directory /etc/vbox found, but ignored. VirtualBox
-+	         configuration files are stored in /usr/local/etc/vbox/.
++	         configuration files are stored in %%LOCALBASE%%/etc/vbox/.
 +	EOH
 +fi
 +
diff --git a/emulators/virtualbox-ose/files/patch-src_VBox_HostDrivers_adpctl_VBoxNetAdpCtl.cpp b/emulators/virtualbox-ose/files/patch-src_VBox_HostDrivers_adpctl_VBoxNetAdpCtl.cpp
--- a/emulators/virtualbox-ose/files/patch-src_VBox_HostDrivers_adpctl_VBoxNetAdpCtl.cpp
+++ b/emulators/virtualbox-ose/files/patch-src_VBox_HostDrivers_adpctl_VBoxNetAdpCtl.cpp
@@ -5,7 +5,7 @@
  *********************************************************************************************************************************/
  
 -#define VBOX_GLOBAL_NETWORK_CONFIG_PATH "/etc/vbox/networks.conf"
-+#define VBOX_GLOBAL_NETWORK_CONFIG_PATH "/usr/local/etc/vbox/networks.conf"
++#define VBOX_GLOBAL_NETWORK_CONFIG_PATH "%%LOCALBASE%%/etc/vbox/networks.conf"
  #define VBOXNET_DEFAULT_IPV4MASK "255.255.255.0"
  
  class NetworkAddress