diff --git a/biology/prodigy-lig/Makefile b/biology/prodigy-lig/Makefile
index 220bf77a33c7..c6a6a72badf5 100644
--- a/biology/prodigy-lig/Makefile
+++ b/biology/prodigy-lig/Makefile
@@ -1,24 +1,25 @@
 PORTNAME=	prodigy-lig
 DISTVERSIONPREFIX=	v
-DISTVERSION=	1.1.0
+DISTVERSION=	1.1.1
 CATEGORIES=	biology python
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Prediction of protein-small molecule binding affinities
 WWW=		https://nestor.science.uu.nl/prodigy/lig
 
 LICENSE=	APACHE20
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
 BUILD_DEPENDS=	${PYNUMPY} \
-		${PYTHON_PKGNAMEPREFIX}biopython>0:biology/py-biopython@${PY_FLAVOR}
+		${PYTHON_PKGNAMEPREFIX}biopython>0:biology/py-biopython@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}poetry-core>0:devel/py-poetry-core@${PY_FLAVOR}
 
 USES=		gmake python
-USE_PYTHON=	distutils noflavors autoplist
+USE_PYTHON=	pep517 noflavors autoplist
 
 USE_GITHUB=	yes
 GH_ACCOUNT=	haddocking
 
 NO_ARCH=	yes
 
 .include <bsd.port.mk>
diff --git a/biology/prodigy-lig/distinfo b/biology/prodigy-lig/distinfo
index a934c718530b..fb14a3af4599 100644
--- a/biology/prodigy-lig/distinfo
+++ b/biology/prodigy-lig/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1711007516
-SHA256 (haddocking-prodigy-lig-v1.1.0_GH0.tar.gz) = 66991015aff86fee6f5cbbc7c28107843083223d3d1aa18b67a658f2bd54bcd4
-SIZE (haddocking-prodigy-lig-v1.1.0_GH0.tar.gz) = 156624
+TIMESTAMP = 1714194540
+SHA256 (haddocking-prodigy-lig-v1.1.1_GH0.tar.gz) = 22a6ed0cbec84dcc2d0f8b0bc8206c2e6c14a057307486648fc0919d9eca63ab
+SIZE (haddocking-prodigy-lig-v1.1.1_GH0.tar.gz) = 156208