diff --git a/biology/hyphy/Makefile b/biology/hyphy/Makefile
index aeaa0f7c0676..9e96954a676c 100644
--- a/biology/hyphy/Makefile
+++ b/biology/hyphy/Makefile
@@ -1,29 +1,29 @@
 PORTNAME=	hyphy
-DISTVERSION=	2.5.41
+DISTVERSION=	2.5.42
 CATEGORIES=	biology
 
 MAINTAINER=	jrm@FreeBSD.org
 COMMENT=	Hypothesis testing using Phylogenies
 WWW=		https://www.hyphy.org/
 
 LICENSE=	MIT
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
 .if !exists(/usr/include/omp.h)
 BROKEN=		requires OpenMP support that is missing on this architecture
 .endif
 
 ONLY_FOR_ARCHS=	aarch64 amd64 armv7 i386 powerpc64le powerpc64 powerpc
 
 LIB_DEPENDS=	libcurl.so:ftp/curl
 
 USES=		cmake localbase:ldflags
 USE_GITHUB=	yes
 GH_ACCOUNT=	veg
 
 OPTIONS_DEFINE=	AVX
 AVX_DESC=	Advanced vector extensions support
 
 AVX_CMAKE_OFF=	-DNOAVX:BOOL=ON
 
 .include <bsd.port.mk>
diff --git a/biology/hyphy/distinfo b/biology/hyphy/distinfo
index 645e16497700..668938dee708 100644
--- a/biology/hyphy/distinfo
+++ b/biology/hyphy/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1659816156
-SHA256 (veg-hyphy-2.5.41_GH0.tar.gz) = 959c18d0b9a65d21cfb667585ec34e1b4a5fd8092112cbd8489c0efa4ce2e7f2
-SIZE (veg-hyphy-2.5.41_GH0.tar.gz) = 5636184
+TIMESTAMP = 1663619549
+SHA256 (veg-hyphy-2.5.42_GH0.tar.gz) = 7b83694fdc42f9c1ae39b1b80f1c614e6f23e2997a32c147494eadc242a81617
+SIZE (veg-hyphy-2.5.42_GH0.tar.gz) = 5634392