diff --git a/devel/py-grpcio/Makefile b/devel/py-grpcio/Makefile
index 1d20a2194167..7f281a97430d 100644
--- a/devel/py-grpcio/Makefile
+++ b/devel/py-grpcio/Makefile
@@ -1,30 +1,30 @@
 PORTNAME=	grpcio
-PORTVERSION=	1.47.0
+PORTVERSION=	1.48.0
 CATEGORIES=	devel python
 MASTER_SITES=	CHEESESHOP
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	vanilla@FreeBSD.org
 COMMENT=	HTTP/2-based RPC framework
 
 LICENSE=	APACHE20
 
 RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}protobuf>=3:devel/py-protobuf@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}six>1:devel/py-six@${PY_FLAVOR}
 LIB_DEPENDS=	libcares.so:dns/c-ares
 
 USES=		compiler:c++11-lib localbase:ldflags python:3.6+ ssl
 USE_PYTHON=	autoplist cython distutils
 MAKE_ENV+=	GRPC_PYTHON_BUILD_SYSTEM_CARES=true \
 		GRPC_PYTHON_BUILD_SYSTEM_OPENSSL=true \
 		GRPC_PYTHON_BUILD_SYSTEM_ZLIB=true
 LDFLAGS+=	-lcares
 
 post-patch:
 	@${RM} ${WRKSRC}/src/python/grpcio/grpc/_cython/cygrpc.cpp
 
 post-install:
 	${STRIP_CMD} ${STAGEDIR}${PYTHONPREFIX_SITELIBDIR}/grpc/_cython/cygrpc*.so
 	${REINPLACE_CMD} -e 's|^.*so$$|${PYTHONPREFIX_SITELIBDIR}/grpc/_cython/cygrpc${PYTHON_EXT_SUFFIX}.so|' ${_PYTHONPKGLIST}
 
 .include <bsd.port.mk>
diff --git a/devel/py-grpcio/distinfo b/devel/py-grpcio/distinfo
index 68c60dc26e3d..a22872b21071 100644
--- a/devel/py-grpcio/distinfo
+++ b/devel/py-grpcio/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1656041549
-SHA256 (grpcio-1.47.0.tar.gz) = 5dbba95fab9b35957b4977b8904fc1fa56b302f9051eff4d7716ebb0c087f801
-SIZE (grpcio-1.47.0.tar.gz) = 21892877
+TIMESTAMP = 1659187266
+SHA256 (grpcio-1.48.0.tar.gz) = eaf4bb73819863440727195411ab3b5c304f6663625e66f348e91ebe0a039306
+SIZE (grpcio-1.48.0.tar.gz) = 21979601
diff --git a/devel/py-grpcio/files/patch-third__party_abseil-cpp_absl_base_internal_unscaledcycleclock.cc b/devel/py-grpcio/files/patch-third__party_abseil-cpp_absl_base_internal_unscaledcycleclock.cc
deleted file mode 100644
index 5d806419494c..000000000000
--- a/devel/py-grpcio/files/patch-third__party_abseil-cpp_absl_base_internal_unscaledcycleclock.cc
+++ /dev/null
@@ -1,14 +0,0 @@
---- third_party/abseil-cpp/absl/base/internal/unscaledcycleclock.cc.orig	2020-08-08 21:50:49 UTC
-+++ third_party/abseil-cpp/absl/base/internal/unscaledcycleclock.cc
-@@ -24,8 +24,10 @@
- #ifdef __GLIBC__
- #include <sys/platform/ppc.h>
- #elif defined(__FreeBSD__)
--#include <sys/sysctl.h>
-+#include "absl/base/call_once.h"
- #include <sys/types.h>
-+#include <sys/sysctl.h>
-+#include <threads.h>
- #endif
- #endif
- 
diff --git a/devel/py-grpcio/files/patch-third__party_abseil-cpp_absl_debugging_internal_vdso__support.cc b/devel/py-grpcio/files/patch-third__party_abseil-cpp_absl_debugging_internal_vdso__support.cc
deleted file mode 100644
index 8acb0683512f..000000000000
--- a/devel/py-grpcio/files/patch-third__party_abseil-cpp_absl_debugging_internal_vdso__support.cc
+++ /dev/null
@@ -1,12 +0,0 @@
---- third_party/abseil-cpp/absl/debugging/internal/vdso_support.cc.orig	2022-05-18 05:37:03 UTC
-+++ third_party/abseil-cpp/absl/debugging/internal/vdso_support.cc
-@@ -51,7 +51,9 @@
- #endif
- 
- #if defined(__FreeBSD__)
-+#if defined(__ELF_WORD_SIZE) && __ELF_WORD_SIZE == 64
- using Elf64_auxv_t = Elf64_Auxinfo;
-+#endif
- using Elf32_auxv_t = Elf32_Auxinfo;
- #endif
-