diff --git a/biology/py-ont-fast5-api/Makefile b/biology/py-ont-fast5-api/Makefile
index d998d68a0e04..79879d97e612 100644
--- a/biology/py-ont-fast5-api/Makefile
+++ b/biology/py-ont-fast5-api/Makefile
@@ -1,42 +1,42 @@
 PORTNAME=	ont-fast5-api
 DISTVERSIONPREFIX=	release_
-DISTVERSION=	4.0.0
+DISTVERSION=	4.0.2
 CATEGORIES=	biology python
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	jwb@FreeBSD.org
 COMMENT=	Interface to HDF5 files in Oxford Nanopore .fast5 format
 
 LICENSE=	MPL20
 LICENSE_FILE=	${WRKSRC}/LICENSE.md
 
 LIB_DEPENDS=	libvbz_hdf_plugin.so:archivers/vbz-compression
 RUN_DEPENDS=	${PYNUMPY} \
 		${PYTHON_PKGNAMEPREFIX}h5py>=2.2.0:science/py-h5py@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}six>0:devel/py-six@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}progressbar>0:misc/py-progressbar@${PY_FLAVOR}
 TEST_DEPENDS=	${PYTHON_PKGNAMEPREFIX}pip>=0:devel/py-pip@${PY_FLAVOR}
 
 USES=		python
-USE_PYTHON=	autoplist distutils
+USE_PYTHON=	autoplist concurrent distutils
 USE_GITHUB=	yes
 
 GH_ACCOUNT=	nanoporetech
 GH_PROJECT=	ont_fast5_api
 
 NO_ARCH=	yes
 NO_BUILD=	yes
 
 post-patch:
 	${RM} ${WRKSRC}/ont_fast5_api/vbz_plugin/*
 
 pre-configure:
 	@${REINPLACE_CMD} -e 's|progressbar33|progressbar|g' \
 		${WRKSRC}/setup.py \
 		${WRKSRC}/README.rst \
 		${WRKSRC}/ont_fast5_api/conversion_tools/conversion_utils.py
 
 do-test:
 	@cd ${WRKSRC} && ${PYTHON_CMD} ${PYDISTUTILS_SETUP} test
 
 .include <bsd.port.mk>
diff --git a/biology/py-ont-fast5-api/distinfo b/biology/py-ont-fast5-api/distinfo
index 9156cd8912ef..d6298ee5ba57 100644
--- a/biology/py-ont-fast5-api/distinfo
+++ b/biology/py-ont-fast5-api/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1628770827
-SHA256 (nanoporetech-ont_fast5_api-release_4.0.0_GH0.tar.gz) = 7f9b3fa0f814ff38c30e9cb21971ec61e2b3fd52fb166a8404c21bf25679e0ab
-SIZE (nanoporetech-ont_fast5_api-release_4.0.0_GH0.tar.gz) = 4081125
+TIMESTAMP = 1648128656
+SHA256 (nanoporetech-ont_fast5_api-release_4.0.2_GH0.tar.gz) = c078dc0d20b02cd9807105415f259e099f1adc8b922d67a1a9fe04321c098361
+SIZE (nanoporetech-ont_fast5_api-release_4.0.2_GH0.tar.gz) = 4082466
diff --git a/biology/py-ont-fast5-api/files/patch-setup.py b/biology/py-ont-fast5-api/files/patch-setup.py
new file mode 100644
index 000000000000..a29c7326d3b5
--- /dev/null
+++ b/biology/py-ont-fast5-api/files/patch-setup.py
@@ -0,0 +1,11 @@
+--- setup.py.orig	2022-03-25 16:23:32 UTC
++++ setup.py
+@@ -35,7 +35,7 @@ setup(name=__pkg_name__.replace("_", "-"),
+       version=get_version(),
+       url='https://github.com/nanoporetech/{}'.format(__pkg_name__),
+       install_requires=installation_requirements,
+-      packages=find_packages(),
++      packages=find_packages(exclude=['test']),
+       package_data={__pkg_name__: ['vbz_plugin/*.so', 'vbz_plugin/*.dylib', 'vbz_plugin/*.dll']},
+       python_requires='>=3.6',
+       entry_points={'console_scripts': [