diff --git a/biology/vsearch/Makefile b/biology/vsearch/Makefile
index 5489406ee279..a13b51ab498b 100644
--- a/biology/vsearch/Makefile
+++ b/biology/vsearch/Makefile
@@ -1,30 +1,29 @@
 PORTNAME=		vsearch
 DISTVERSIONPREFIX=	v
-DISTVERSION=		2.17.0
+DISTVERSION=		2.17.1
 CATEGORIES=		biology
 
 MAINTAINER=	jwb@FreeBSD.org
 COMMENT=	Versatile open-source tool for metagenomics
 
 LICENSE=	GPLv3
 LICENSE_FILE=	${WRKSRC}/LICENSE.txt
 
-# Note: For PPC need power8 or later, little endian
-ONLY_FOR_ARCHS=		aarch64 amd64
+ONLY_FOR_ARCHS=		aarch64 amd64 powerpc64le
 ONLY_FOR_ARCHS_REASON=	Explicitly enumerated by upstream developers
 
 LIB_DEPENDS=	libsysinfo.so:devel/libsysinfo
 
 USES=		autoreconf ghostscript:build gmake localbase
 USE_GITHUB=	yes
 
 GH_ACCOUNT=	torognes
 GNU_CONFIGURE=	yes
 
 PLIST_FILES=	bin/vsearch man/man1/vsearch.1.gz
 PORTDOCS=	*
 
 OPTIONS_DEFINE=	DOCS
 OPTIONS_SUB=	yes
 
 .include <bsd.port.mk>
diff --git a/biology/vsearch/distinfo b/biology/vsearch/distinfo
index 480e0f285a1d..6fe700db2278 100644
--- a/biology/vsearch/distinfo
+++ b/biology/vsearch/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1617114740
-SHA256 (torognes-vsearch-v2.17.0_GH0.tar.gz) = 8c783c27dbdd416f48bd1b7317c1669468f3e7ebe7717b84de6794a2c1e998b9
-SIZE (torognes-vsearch-v2.17.0_GH0.tar.gz) = 246359
+TIMESTAMP = 1623856296
+SHA256 (torognes-vsearch-v2.17.1_GH0.tar.gz) = cee02a1fceb919db8916c6f114926a11166db15d2da79c1c1f680285435d39bc
+SIZE (torognes-vsearch-v2.17.1_GH0.tar.gz) = 249268