diff --git a/net/py-kombu/Makefile b/net/py-kombu/Makefile
index 2e768a708d3e..1059af90e965 100644
--- a/net/py-kombu/Makefile
+++ b/net/py-kombu/Makefile
@@ -1,35 +1,35 @@
 PORTNAME=	kombu
-PORTVERSION=	4.6.11
+PORTVERSION=	5.3.5
 CATEGORIES=	net python
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	olgeni@FreeBSD.org
 COMMENT=	AMQP messaging framework for Python
 WWW=		https://kombu.readthedocs.org/
 
 LICENSE=	BSD3CLAUSE
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
-RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}amqp>=2.6.0<2.7:net/py-amqp@${PY_FLAVOR}
+RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}amqp>=5.1.1,<6.0.0:net/py-amqp@${PY_FLAVOR}
 
 USES=		python
 USE_PYTHON=	autoplist distutils
 
 NO_ARCH=	yes
 
 OPTIONS_DEFINE=	BOTO MONGODB REDIS SQLALCHEMY ZMQ
 
 BOTO_DESC=	Include AWS transport support
 MONGODB_DESC=	Include MongoDB transport support
 REDIS_DESC=	Include Redis transport support
 SQLALCHEMY_DESC=Include SQLAlchemy transport support
 ZMQ_DESC=	Include ZMQ transport support
 
 BOTO_RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}boto>=2.6.0:devel/py-boto@${PY_FLAVOR}
 MONGODB_RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}pymongo>=3.3.0:databases/py-pymongo@${PY_FLAVOR}
 REDIS_RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}redis>0:databases/py-redis@${PY_FLAVOR}
 SQLALCHEMY_RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}sqlalchemy10>0:databases/py-sqlalchemy10@${PY_FLAVOR}
 ZMQ_RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}pyzmq>=13.1.0:net/py-pyzmq@${PY_FLAVOR}
 
 .include <bsd.port.mk>
diff --git a/net/py-kombu/distinfo b/net/py-kombu/distinfo
index d153abece351..8133d9189046 100644
--- a/net/py-kombu/distinfo
+++ b/net/py-kombu/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1613397544
-SHA256 (kombu-4.6.11.tar.gz) = ca1b45faac8c0b18493d02a8571792f3c40291cf2bcf1f55afed3d8f3aa7ba74
-SIZE (kombu-4.6.11.tar.gz) = 406968
+TIMESTAMP = 1707143486
+SHA256 (kombu-5.3.5.tar.gz) = 30e470f1a6b49c70dc6f6d13c3e4cc4e178aa6c469ceb6bcd55645385fc84b93
+SIZE (kombu-5.3.5.tar.gz) = 438460