diff --git a/biology/fastp/Makefile b/biology/fastp/Makefile
index 7af865fb935a..abff6e966321 100644
--- a/biology/fastp/Makefile
+++ b/biology/fastp/Makefile
@@ -1,27 +1,27 @@
 PORTNAME=		fastp
 DISTVERSIONPREFIX=	v
-DISTVERSION=		0.24.1
+DISTVERSION=		0.24.3
 CATEGORIES=		biology
 
 MAINTAINER=	jwb@FreeBSD.org
 COMMENT=	Ultra-fast all-in-one FASTQ preprocessor
 WWW=		https://github.com/OpenGene/fastp
 
 LICENSE=	MIT
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
 LIB_DEPENDS=	libdeflate.so:archivers/libdeflate \
 		libisal.so:devel/isa-l
 
 USES=		gmake localbase:ldflags
 USE_GITHUB=	yes
 
 GH_ACCOUNT=	OpenGene
 
 ALL_TARGET=	fastp
 PLIST_FILES=	bin/fastp
 
 post-install:
 	${STRIP_CMD} ${STAGEDIR}${PREFIX}/bin/fastp
 
 .include <bsd.port.mk>
diff --git a/biology/fastp/distinfo b/biology/fastp/distinfo
index d33c3c0986a6..746034000671 100644
--- a/biology/fastp/distinfo
+++ b/biology/fastp/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1744893121
-SHA256 (OpenGene-fastp-v0.24.1_GH0.tar.gz) = dd8a1b7e0410a800f80939e4d14b116e90bbec83ef7294a5f13fdaaba3fcc719
-SIZE (OpenGene-fastp-v0.24.1_GH0.tar.gz) = 164307
+TIMESTAMP = 1748528789
+SHA256 (OpenGene-fastp-v0.24.3_GH0.tar.gz) = fadc9068847227b8cba2147d0202633fc16d85a91f7457ea94f7931bfaf91f58
+SIZE (OpenGene-fastp-v0.24.3_GH0.tar.gz) = 164518