diff --git a/biology/py-bigwig/Makefile b/biology/py-bigwig/Makefile
index ab33b4650777..a7c2f9c5321f 100644
--- a/biology/py-bigwig/Makefile
+++ b/biology/py-bigwig/Makefile
@@ -1,21 +1,21 @@
 PORTNAME=	pyBigWig
 DISTVERSION=	0.3.18
 CATEGORIES=	biology python
 MASTER_SITES=	CHEESESHOP
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	jwb@FreeBSD.org
 COMMENT=	Python access to bigWig files using libBigWig
 
 LICENSE=	MIT
 LICENSE_FILE=	${WRKSRC}/LICENSE.txt
 
 LIB_DEPENDS=	libcurl.so:ftp/curl
 
 USES=		localbase python
 USE_PYTHON=	autoplist distutils
 
 post-install:
-	@${STRIP_CMD} ${STAGEDIR}${PYTHON_SITELIBDIR}/pyBigWig.so
+	@${STRIP_CMD} ${STAGEDIR}${PYTHONPREFIX_SITELIBDIR}/pyBigWig*.so
 
 .include <bsd.port.mk>