diff --git a/science/clipper/Makefile b/science/clipper/Makefile
index d586cc96f44a..a2af4dfcf222 100644
--- a/science/clipper/Makefile
+++ b/science/clipper/Makefile
@@ -1,26 +1,26 @@
 PORTNAME=	clipper
 DISTVERSION=	2.1.20180802
-PORTREVISION=	4
+PORTREVISION=	5
 CATEGORIES=	science
 MASTER_SITES=	https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/dependencies/
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Libraries for the organisation of crystallographic data
 WWW=		http://www.ysbl.york.ac.uk/~cowtan/clipper/
 
 LICENSE=	LGPL3
 LICENSE_FILE=	${WRKSRC}/COPYING
 
 LIB_DEPENDS=	libccp4c.so:science/libccp4 \
 		libmmdb2.so:science/mmdb2 \
 		libsfftw.so:math/fftw-float
 
 USES=		compiler:c++11-lang fortran gmake libtool localbase:ldflags
 GNU_CONFIGURE=	yes
 CONFIGURE_ARGS=	--enable-shared --disable-static \
 		--enable-phs --enable-cns --enable-mmdb --enable-minimol --enable-cif --enable-ccp4 --enable-fortran
 USE_LDCONFIG=	yes
 
 WRKSRC=		${WRKDIR}/${PORTNAME}-${DISTVERSION:C/\.[0-9]+$//}
 
 .include <bsd.port.mk>
diff --git a/science/libccp4/Makefile b/science/libccp4/Makefile
index 6173f170f825..ae02303c8663 100644
--- a/science/libccp4/Makefile
+++ b/science/libccp4/Makefile
@@ -1,33 +1,32 @@
 PORTNAME=	libccp4
-DISTVERSION=	6.5.1
-PORTREVISION=	5
+DISTVERSION=	8.0.0
 CATEGORIES=	science education
-MASTER_SITES=	ftp://ftp.ccp4.ac.uk/opensource/
+MASTER_SITES=	https://ftp.ccp4.ac.uk/opensource/
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Protein X-ray crystallography toolkit
 WWW=		https://www.ccp4.ac.uk/
 
 LICENSE=	GPLv3 LGPL3
 LICENSE_COMB=	dual
 LICENSE_FILE_GPLv3=	${WRKSRC}/COPYING
 LICENSE_FILE_LGPL3=	${WRKSRC}/COPYING.LESSER
 
 BROKEN_aarch64=		ccp4/ccp4_sysdep.h:244:4: error: "Can't determine machine number format"
 
 LIB_DEPENDS=	libmmdb2.so:science/mmdb2
 
 USES=		fortran gmake libtool localbase:ldflags
 GNU_CONFIGURE=	yes
 CONFIGURE_ARGS=	--enable-shared --disable-static
 INSTALL_TARGET=	install-strip
 USE_LDCONFIG=	yes
 
 CFLAGS+=	-fPIC
 FFLAGS+=	-fPIC -std=legacy
 
 post-configure:
 	${REINPLACE_CMD} -e 's| -Wl,--as-needed||; s| -Wl,--no-as-needed||' ${WRKSRC}/Makefile
 	${REINPLACE_CMD} -e 's|^archive_cmds=|wl="-Wl,"; archive_cmds=|' ${WRKSRC}/libtool # wl is missing otherwise for some reason
 
 .include <bsd.port.mk>
diff --git a/science/libccp4/distinfo b/science/libccp4/distinfo
index 603fa7715ef4..1b4305b39fe8 100644
--- a/science/libccp4/distinfo
+++ b/science/libccp4/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1531007069
-SHA256 (libccp4-6.5.1.tar.gz) = 280b473d950cdf8837ef66147ec581104298b892399bd856f13b096f2395dbe5
-SIZE (libccp4-6.5.1.tar.gz) = 947521
+TIMESTAMP = 1737971420
+SHA256 (libccp4-8.0.0.tar.gz) = cb813ae86612a0866329deab7cee96eac573d81be5b240341d40f9ad5322ff2d
+SIZE (libccp4-8.0.0.tar.gz) = 937534
diff --git a/science/libccp4/pkg-plist b/science/libccp4/pkg-plist
index be093c7c61b1..cd5d6794373b 100644
--- a/science/libccp4/pkg-plist
+++ b/science/libccp4/pkg-plist
@@ -1,44 +1,44 @@
 include/ccp4/ccp4_array.h
 include/ccp4/ccp4_errno.h
 include/ccp4/ccp4_file_err.h
 include/ccp4/ccp4_fortran.h
 include/ccp4/ccp4_general.h
 include/ccp4/ccp4_parser.h
 include/ccp4/ccp4_program.h
 include/ccp4/ccp4_spg.h
 include/ccp4/ccp4_sysdep.h
 include/ccp4/ccp4_types.h
 include/ccp4/ccp4_unitcell.h
 include/ccp4/ccp4_utils.h
 include/ccp4/ccp4_vars.h
 include/ccp4/cmap_data.h
 include/ccp4/cmap_errno.h
 include/ccp4/cmap_header.h
 include/ccp4/cmap_labels.h
 include/ccp4/cmap_skew.h
 include/ccp4/cmap_stats.h
 include/ccp4/cmaplib.h
 include/ccp4/cmaplib_f.h
 include/ccp4/cmtzlib.h
 include/ccp4/csymlib.h
 include/ccp4/cvecmat.h
 include/ccp4/library_file.h
 include/ccp4/mtzdata.h
 include/ccp4/overview.h
 include/ccp4/pack_c.h
 include/ccp4/w32mvs.h
 lib/libccp4c.so
 lib/libccp4c.so.0
 lib/libccp4c.so.0.0.0
 lib/libccp4f.so
 lib/libccp4f.so.0
 lib/libccp4f.so.0.0.0
-libdata/pkgconfig/libccp4c.pc
-libdata/pkgconfig/libccp4f.pc
+libdata/pkgconfig/ccp4c.pc
+libdata/pkgconfig/ccp4f.pc
 share/atomsf.lib
 share/atomsf_electron.lib
 share/atomsf_neutron.lib
 share/ccp4/ccp4-config.cmake
 share/font84.ascii
 share/syminfo.lib
 share/symop.lib
diff --git a/science/libssm/Makefile b/science/libssm/Makefile
index 1454e1825594..8cd75e00dad3 100644
--- a/science/libssm/Makefile
+++ b/science/libssm/Makefile
@@ -1,24 +1,24 @@
 PORTNAME=	libssm
 DISTVERSION=	1.4.0
-PORTREVISION=	3
+PORTREVISION=	4
 CATEGORIES=	science
 MASTER_SITES=	ftp://ftp.ccp4.ac.uk/opensource/
 DISTNAME=	ssm-${DISTVERSION}
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	C++ toolkit for superposition of macromolecules
 WWW=		https://launchpad.net/ssm
 
 LICENSE=	GPLv3
 LICENSE_FILE=	${WRKSRC}/COPYING
 
 LIB_DEPENDS=	libccp4c.so:science/libccp4 \
 		libmmdb2.so:science/mmdb2
 
 USES=		gmake libtool localbase:ldflags
 GNU_CONFIGURE=	yes
 CONFIGURE_ARGS=	--enable-shared --disable-static --enable-ccp4 --with-mmdb=${LOCALBASE}
 INSTALL_TARGET=	install-strip
 USE_LDCONFIG=	yes
 
 .include <bsd.port.mk>