diff --git a/devel/py-spyder-kernels/Makefile b/devel/py-spyder-kernels/Makefile
index 7359c863310b..1d5cd4968b73 100644
--- a/devel/py-spyder-kernels/Makefile
+++ b/devel/py-spyder-kernels/Makefile
@@ -1,53 +1,54 @@
 # Created by: Rainer Hurling <rhurlin@gwdg.de>
 
 PORTNAME=	spyder-kernels
-PORTVERSION=	2.2.0
+PORTVERSION=	2.2.1
 CATEGORIES=	devel python
 MASTER_SITES=	CHEESESHOP
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	rhurlin@FreeBSD.org
 COMMENT=	Jupyter kernels for the Spyder console
 
 LICENSE=	MIT
 LICENSE_FILE=	${WRKSRC}/LICENSE.txt
 
-# Change to devel/py-ipykernel v6.x, if available
+# Change to devel/py-ipykernel v6.x, when devel/py-ipyparallel
+# and devel/py-jupyter-client have switched from 5.x to 6.x
 RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}cloudpickle>0:devel/py-cloudpickle@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}ipykernel5>0:devel/py-ipykernel5@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}ipyparallel>0:devel/py-ipyparallel@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}ipython>0:devel/ipython@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}jupyter-client>0:devel/py-jupyter-client@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pyzmq>0:net/py-pyzmq@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}traitlets>0:devel/py-traitlets@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}wurlitzer>0:misc/py-wurlitzer@${PY_FLAVOR}
 TEST_DEPENDS=	${PYNUMPY} \
 		${PYTHON_PKGNAMEPREFIX}codecov>0:devel/py-codecov@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}cython>0:lang/cython@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}dask>0:devel/py-dask@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}distributed>0:devel/py-distributed@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}flaky>0:devel/py-flaky@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}ipython_genutils>0:devel/py-ipython_genutils@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}matplotlib>0:math/py-matplotlib@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}mock>0:devel/py-mock@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pandas>0:math/py-pandas@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pillow>0:graphics/py-pillow@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pytest>0:devel/py-pytest@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pytest-cov>0:devel/py-pytest-cov@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pytest-forked>0:devel/py-pytest-forked@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pytest-mock>0:devel/py-pytest-mock@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pytest-timeout>0:devel/py-pytest-timeout@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pytest-xdist>0:devel/py-pytest-xdist@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}scipy>0:science/py-scipy@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}xarray>0:devel/py-xarray@${PY_FLAVOR}
 
 USES=		python:3.7+
 USE_PYTHON=	autoplist concurrent distutils
 
 NO_ARCH=	yes
 
 # test target currently not functional :(
 do-test:
 	@cd ${WRKSRC} && ${PYTHON_CMD} -m pytest -v -rs -o addopts=
 
 .include <bsd.port.mk>
diff --git a/devel/py-spyder-kernels/distinfo b/devel/py-spyder-kernels/distinfo
index 25f9fc714920..ee45110cbf9d 100644
--- a/devel/py-spyder-kernels/distinfo
+++ b/devel/py-spyder-kernels/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1637684134
-SHA256 (spyder-kernels-2.2.0.tar.gz) = 6b19ea224f183dbff8ff0031bee35ae6b5b3a6eef4aa84cfab04e3bc3e304b91
-SIZE (spyder-kernels-2.2.0.tar.gz) = 67587
+TIMESTAMP = 1642147542
+SHA256 (spyder-kernels-2.2.1.tar.gz) = 574ee1bd03f7236b9f9dacae34936a0625cd67ccfe3df11fec69f26889a0b866
+SIZE (spyder-kernels-2.2.1.tar.gz) = 68567