diff --git a/x11-toolkits/pangomm/Makefile b/x11-toolkits/pangomm/Makefile
index f9ddaf64ed79..f948992abb1b 100644
--- a/x11-toolkits/pangomm/Makefile
+++ b/x11-toolkits/pangomm/Makefile
@@ -1,42 +1,25 @@
 PORTNAME=	pangomm
-PORTVERSION=	2.40.1
-PORTREVISION?=	6
+PORTVERSION=	2.46.4
 CATEGORIES=	x11-toolkits
 MASTER_SITES=	GNOME
-DIST_SUBDIR=	gnome2
+DIST_SUBDIR=	gnome
 
 MAINTAINER=	gnome@FreeBSD.org
 COMMENT=	C++ wrapper for Pango
-WWW=		http://gtkmm.sourceforge.net/
+WWW=		https://www.gtkmm.org/
 
 LICENSE=	LGPL21
 
-USES=		tar:xz
-
-.if !defined(REFERENCE_PORT)
-PORTSCOUT=	limitw:1,even
-
-USES+=		compiler:c++11-lang gmake gnome libtool localbase pathfix \
-		pkgconfig
-USE_CXXSTD=	c++11
+USES=		compiler:c++11-lang gnome localbase meson pkgconfig \
+		python:build tar:xz
 USE_GNOME=	cairomm glibmm pango
-GNU_CONFIGURE=	yes
-USE_LDCONFIG=	yes
-CONFIGURE_ARGS=	--disable-documentation \
-		--enable-static=yes
-INSTALL_TARGET=	install-strip
-BINARY_WRAPPERS=	gm4
 
-PLIST_SUB=	VERSION="2.4" API_VERSION="1.4"
+USE_LDCONFIG=	yes
+MESON_ARGS=	-Ddefault_library=both
+BINARY_ALIAS=	python3=${PYTHON_CMD}
 
-post-patch:
-.for d in tests
-	@${REINPLACE_CMD} -e '/^SUBDIRS =/s/${d}//' \
-		${WRKSRC}/Makefile.in
-.endfor
+# 2.48 and later are incompatible
+PORTSCOUT=	limit:^2\.46
+PLIST_SUB=	API_VERSION=1.4
 
 .include <bsd.port.mk>
-
-.else
-PORTSCOUT=	ignore:1
-.endif
diff --git a/x11-toolkits/pangomm/distinfo b/x11-toolkits/pangomm/distinfo
index 426a001745c3..6ba4ec5cfcbb 100644
--- a/x11-toolkits/pangomm/distinfo
+++ b/x11-toolkits/pangomm/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1491167697
-SHA256 (gnome2/pangomm-2.40.1.tar.xz) = 9762ee2a2d5781be6797448d4dd2383ce14907159b30bc12bf6b08e7227be3af
-SIZE (gnome2/pangomm-2.40.1.tar.xz) = 810384
+TIMESTAMP = 1733426036
+SHA256 (gnome/pangomm-2.46.4.tar.xz) = b92016661526424de4b9377f1512f59781f41fb16c9c0267d6133ba1cd68db22
+SIZE (gnome/pangomm-2.46.4.tar.xz) = 695088
diff --git a/x11-toolkits/pangomm/files/patch-pango_pangomm_attributes.h b/x11-toolkits/pangomm/files/patch-pango_pangomm_attributes.h
deleted file mode 100644
index 70e3f057e9f6..000000000000
--- a/x11-toolkits/pangomm/files/patch-pango_pangomm_attributes.h
+++ /dev/null
@@ -1,22 +0,0 @@
-https://gitlab.gnome.org/GNOME/pangomm/-/commit/a8ab02ac9b96
-https://gitlab.gnome.org/GNOME/pangomm/-/commit/c098f35144ff
-
-attrlist.cc:38:20: error: use of undeclared identifier 'pango_parse_markup'
-  gboolean bTest = pango_parse_markup(markup_text.c_str(), -1 /* means null-terminated */, accel_marker,
-                   ^
-attrlist.cc:65:20: error: use of undeclared identifier 'pango_parse_markup'
-  gboolean bTest = pango_parse_markup(markup_text.c_str(), -1 /* means null-terminated */, accel_marker,
-                   ^
-
---- pango/pangomm/attributes.h.orig	2016-08-19 13:58:37 UTC
-+++ pango/pangomm/attributes.h
-@@ -30,6 +30,9 @@
- #include <pangomm/color.h>
- #include <pangomm/fontdescription.h>
- #include <pango/pango-attributes.h>
-+#if __has_include(<pango/pango-markup.h>)
-+#include <pango/pango-markup.h>
-+#endif
- #include <glibmm/slisthandle.h>
- 
- 
diff --git a/x11-toolkits/pangomm/files/patch-tools_extra__defs__gen_meson.build b/x11-toolkits/pangomm/files/patch-tools_extra__defs__gen_meson.build
new file mode 100644
index 000000000000..f7fcf0b9ca7f
--- /dev/null
+++ b/x11-toolkits/pangomm/files/patch-tools_extra__defs__gen_meson.build
@@ -0,0 +1,10 @@
+--- tools/extra_defs_gen/meson.build.orig	2021-12-06 18:18:10 UTC
++++ tools/extra_defs_gen/meson.build
+@@ -7,6 +7,7 @@
+ glibmm_generate_extra_defs_dep = cpp_compiler.find_library(
+   'glibmm_generate_extra_defs@0@-2.68'.format(msvc14x_toolset_ver),
+   required: glibmm_dep.type_name() != 'internal',
++  dirs: join_paths(get_option('prefix'), get_option('libdir')),
+ )
+ if not glibmm_generate_extra_defs_dep.found()
+   glibmm_generate_extra_defs_dep = dependency(