diff --git a/biology/biosig/Makefile b/biology/biosig/Makefile
index 62d1c621958d..b3ef73bf8f58 100644
--- a/biology/biosig/Makefile
+++ b/biology/biosig/Makefile
@@ -1,35 +1,36 @@
 PORTNAME=	biosig
 DISTVERSION=	2.4.3
+PORTREVISION=	1
 CATEGORIES=	biology
 MASTER_SITES=	SF/${PORTNAME}/BioSig%20for%20C_C%2B%2B/src/
 DISTNAME=	${PORTNAME}-${PORTVERSION}.src
 
 MAINTAINER=	yuri@FreeBSD.org
 COMMENT=	Library for reading and writing different biosignal data format
 WWW=		http://biosig.sourceforge.net/
 
 LICENSE=	GPLv3
 LICENSE_FILE=	${WRKSRC}/COPYING
 
 LIB_DEPENDS=	libb64.so:converters/libb64 \
 		libcholmod.so:math/suitesparse-cholmod \
 		libiconv.so:converters/libiconv \
 		libtinyxml.so:textproc/tinyxml
 
 USES=		gmake iconv localbase:ldflags tar:xz
 USE_LDCONFIG=	yes
 
 WRKSRC=		${WRKDIR}/${PORTNAME}-${DISTVERSION}
 
 GNU_CONFIGURE=	yes
 
 CFLAGS+=	-D__BYTE_ORDER=BYTE_ORDER -D__LITTLE_ENDIAN=LITTLE_ENDIAN -D__BIG_ENDIAN=BIG_ENDIAN \
 		-Dbswap_16=bswap16 -Dbswap_32=bswap32 -Dbswap_64=bswap64
 LDFLAGS+=	-liconv
 
 post-install:
 .for f in bin/biosig_fhir bin/biosig2gdf bin/physicalunits bin/save2gdf lib/libbiosig.so.3
 	@${STRIP_CMD} ${STAGEDIR}${PREFIX}/${f}
 .endfor
 
 .include <bsd.port.mk>
diff --git a/biology/biosig/files/patch-biosig4c++_biosig-dev.h b/biology/biosig/files/patch-biosig4c++_biosig-dev.h
index 39fedc40975c..8a489fdfc0db 100644
--- a/biology/biosig/files/patch-biosig4c++_biosig-dev.h
+++ b/biology/biosig/files/patch-biosig4c++_biosig-dev.h
@@ -1,21 +1,24 @@
---- biosig4c++/biosig-dev.h.orig	2021-08-13 09:17:15 UTC
+--- biosig4c++/biosig-dev.h.orig	2022-10-08 10:54:15 UTC
 +++ biosig4c++/biosig-dev.h
 @@ -35,6 +35,8 @@
  #include <time.h>
  #include "physicalunits.h"
  
 +#include <sys/endian.h>
 +#include <machine/endian.h> // for betoh16, etc.
  
  #ifdef __cplusplus
  extern "C" {
-@@ -549,6 +551,9 @@ HDRTYPE* sopen_extended(const char* FileName, const ch
+@@ -549,6 +551,12 @@ HDRTYPE* sopen_extended(const char* FileName, const ch
  #elif defined(__linux__) 
  #  include <endian.h>
  #  include <byteswap.h>
 +
 +#elif defined(__FreeBSD__) 
 +#  include <machine/endian.h>
++#  define __BIG_ENDIAN _BIG_ENDIAN
++#  define __LITTLE_ENDIAN _LITTLE_ENDIAN
++#  define __BYTE_ORDER _BYTE_ORDER
  
- #elif defined(__GLIBC__)       // for Hurd
- #  include <endian.h>
+ #elif defined(__FreeBSD__)
+ #  include <machine/endian.h>