diff --git a/devel/py-grpcio/Makefile b/devel/py-grpcio/Makefile
index 0da71e883776..b51f58ab4a1f 100644
--- a/devel/py-grpcio/Makefile
+++ b/devel/py-grpcio/Makefile
@@ -1,33 +1,33 @@
 PORTNAME=	grpcio
-PORTVERSION=	1.65.0
+PORTVERSION=	1.65.1
 CATEGORIES=	devel python
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	vanilla@FreeBSD.org
 COMMENT=	HTTP/2-based RPC framework
 WWW=		https://pypi.org/project/grpcio/
 
 LICENSE=	APACHE20
 
 RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}protobuf>=3:devel/py-protobuf@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}six>1:devel/py-six@${PY_FLAVOR}
 LIB_DEPENDS=	libcares.so:dns/c-ares
 
 USES=		compiler:c++11-lib localbase:ldflags python ssl
 BROKEN_SSL=	libressl
 BROKEN_SSL_REASON=	use of undeclared identifier 'X509_STORE_set_get_crl'
 USE_PYTHON=	autoplist cython distutils
 MAKE_ENV+=	GRPC_PYTHON_BUILD_SYSTEM_CARES=true \
 		GRPC_PYTHON_BUILD_SYSTEM_OPENSSL=true \
 		GRPC_PYTHON_BUILD_SYSTEM_ZLIB=true
 LDFLAGS+=	-lcares
 
 post-patch:
 	@${RM} ${WRKSRC}/src/python/grpcio/grpc/_cython/cygrpc.cpp
 
 post-install:
 	${STRIP_CMD} ${STAGEDIR}${PYTHONPREFIX_SITELIBDIR}/grpc/_cython/cygrpc*.so
 	${REINPLACE_CMD} -e 's|^.*so$$|${PYTHONPREFIX_SITELIBDIR}/grpc/_cython/cygrpc${PYTHON_EXT_SUFFIX}.so|' ${_PYTHONPKGLIST}
 
 .include <bsd.port.mk>
diff --git a/devel/py-grpcio/distinfo b/devel/py-grpcio/distinfo
index afcbb2eb4d98..028ac65a69f3 100644
--- a/devel/py-grpcio/distinfo
+++ b/devel/py-grpcio/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1720758858
-SHA256 (grpcio-1.65.0.tar.gz) = 2c7891f66daefc80cce1bed6bc0c2802d26dac46544ba1be79c4e7d85661dd73
-SIZE (grpcio-1.65.0.tar.gz) = 12243603
+TIMESTAMP = 1721532219
+SHA256 (grpcio-1.65.1.tar.gz) = 3c492301988cd720cd145d84e17318d45af342e29ef93141228f9cd73222368b
+SIZE (grpcio-1.65.1.tar.gz) = 12256550