diff --git a/biology/hisat2/Makefile b/biology/hisat2/Makefile
index ae0ad38fbe7d..33d56578fcf8 100644
--- a/biology/hisat2/Makefile
+++ b/biology/hisat2/Makefile
@@ -1,26 +1,27 @@
 PORTNAME=		hisat2
 DISTVERSIONPREFIX=	v
 DISTVERSION=		2.2.1
+PORTREVISION=		1
 CATEGORIES=		biology perl5 python
 
 MAINTAINER=	jwb@FreeBSD.org
 COMMENT=	Alignment program for mapping next-generation sequencing reads
 
 LICENSE=	GPLv3
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
 ONLY_FOR_ARCHS=		amd64
 ONLY_FOR_ARCHS_REASON=	64-bit code, some assembly language
 
 USES=		gmake perl5 python shebangfix
 USE_GITHUB=	yes
 
 SHEBANG_FILES=	hisat2 hisat2-build hisat2-inspect \
 		*.py */*.py */*/*.py */*/*/*.py \
 		scripts/*.sh evaluation/tests/HLA_novel/scripts/*.sh \
 		scripts/*.pl docs_jhu/*.pl
 GH_ACCOUNT=	DaehwanKimLab
 
 CFLAGS+=	-Wno-deprecated-declarations -Wno-char-subscripts
 
 .include <bsd.port.mk>
diff --git a/biology/hisat2/files/patch-util.h b/biology/hisat2/files/patch-util.h
deleted file mode 100644
index 43c3aa88400c..000000000000
--- a/biology/hisat2/files/patch-util.h
+++ /dev/null
@@ -1,11 +0,0 @@
---- util.h.orig	2021-11-26 15:40:17 UTC
-+++ util.h
-@@ -43,7 +43,7 @@ char* itoa10(const T& value, char* result) {
- 	// Only apply negative sign for base 10
- 	if(std::numeric_limits<T>::is_signed) {
- 		// Avoid compiler warning in cases where T is unsigned
--		if (value <= 0 && value != 0) *out++ = '-';
-+		if (value <= 0) *out++ = '-';
- 	}
- 	reverse( result, out );
- 	*out = 0; // terminator