diff --git a/databases/py-mysql-connector-python/Makefile b/databases/py-mysql-connector-python/Makefile
index 9972791452ca..832730f53c7c 100644
--- a/databases/py-mysql-connector-python/Makefile
+++ b/databases/py-mysql-connector-python/Makefile
@@ -1,43 +1,46 @@
 PORTNAME=	mysql-connector-python
 PORTVERSION=	8.1.0
+PORTREVISION=	1
 CATEGORIES=	databases python
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
 MAINTAINER=	bofh@FreeBSD.org
 COMMENT=	MySQL driver written in Python
 WWW=		https://dev.mysql.com/doc/connector-python/en
 
 LICENSE=	GPLv2
 
 BUILD_DEPENDS=	${PY_SETUPTOOLS} \
 		${PYTHON_PKGNAMEPREFIX}wheel>0:devel/py-wheel@${PY_FLAVOR}
-RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}protobuf>=3.11.0:devel/py-protobuf@${PY_FLAVOR}
+RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}protobuf>=4.21.1:devel/py-protobuf@${PY_FLAVOR}
 
 USES=		python
 USE_GITHUB=	yes
 GH_ACCOUNT=	mysql
 USE_PYTHON=	autoplist pep517
 
 NO_ARCH=	yes
 
 PORTSCOUT=	skipv:init
 
 OPTIONS_DEFINE=	COMPRESSION DNS GSSAPI
 
 COMPRESSION_DESC=	Compression Support
 DNS_DESC=		DNS Support
 
 COMPRESSION_RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}lz4>=2.1.6:archivers/py-lz4@${PY_FLAVOR} \
 				${PYTHON_PKGNAMEPREFIX}zstandard>=0.12.0:archivers/py-zstandard@${PY_FLAVOR}
 DNS_RUN_DEPENDS=		${PYTHON_PKGNAMEPREFIX}dnspython>=1.16.0:dns/py-dnspython@${PY_FLAVOR}
 GSSAPI_RUN_DEPENDS=		${PYTHON_PKGNAMEPREFIX}gssapi>=1.6.9:security/py-gssapi@${PY_FLAVOR}
 
 post-patch:
 	@${REINPLACE_CMD} -e 's|"gcc"|"${CC}"|g ; \
 		s|"g++"|"${CXX}"|g' \
 		${WRKSRC}/cpydist/__init__.py
+	@${REINPLACE_CMD} -e 's|protobuf>=4.21.1,<=4.21.12|protobuf>=4.21.1|g' \
+		${WRKSRC}/setup.py
 
 do-test:
 	@(cd ${TEST_WRKSRC} && ${SETENV} ${TEST_ENV} ${PYTHON_CMD} ./unittests.py)
 
 .include <bsd.port.mk>