diff --git a/biology/trimadap/Makefile b/biology/trimadap/Makefile
--- a/biology/trimadap/Makefile
+++ b/biology/trimadap/Makefile
@@ -1,7 +1,7 @@
 PORTNAME=	trimadap
 DISTVERSION=	0.1-3
 DISTVERSIONSUFFIX=	-gddfef21
-PORTREVISION=	1
+PORTREVISION=	2
 CATEGORIES=	biology
 
 MAINTAINER=	jwb@FreeBSD.org
@@ -10,9 +10,14 @@
 
 LICENSE=	GPLv2
 
-ONLY_FOR_ARCHS=		amd64 i386 powerpc64le
+ONLY_FOR_ARCHS=		aarch64 amd64 armv7 i386 powerpc64le
 ONLY_FOR_ARCHS_REASON=	uses hard-coded SSE instructions
 
+aarch64_BUILD_DEPENDS=	${LOCALBASE}/include/sse2neon.h:devel/sse2neon
+armv7_BUILD_DEPENDS=	${aarch64_BUILD_DEPENDS}
+BUILD_DEPENDS+=	${${ARCH}_BUILD_DEPENDS}
+
+USES=		localbase
 USE_GITHUB=	yes
 GH_ACCOUNT=	lh3
 
diff --git a/biology/trimadap/files/patch-ksw.c b/biology/trimadap/files/patch-ksw.c
new file mode 100644
--- /dev/null
+++ b/biology/trimadap/files/patch-ksw.c
@@ -0,0 +1,14 @@
+--- ksw.c.orig	2024-10-15 15:21:11 UTC
++++ ksw.c
+@@ -26,7 +26,11 @@
+ #include <stdlib.h>
+ #include <stdint.h>
+ #include <string.h>
++#if defined(__arm__) || defined(__aarch64__)
++#include <sse2neon.h>
++#else
+ #include <emmintrin.h>
++#endif
+ #include "ksw.h"
+ 
+ #ifdef __GNUC__