diff --git a/sys/cam/ata/ata_da.c b/sys/cam/ata/ata_da.c
--- a/sys/cam/ata/ata_da.c
+++ b/sys/cam/ata/ata_da.c
@@ -2518,7 +2518,16 @@
 			error = ada_zone_cmd(periph, start_ccb, bp, &queue_ccb);
 			if ((error != 0)
 			 || (queue_ccb == 0)) {
+				/*
+				 * g_io_deliver will recurisvely call start
+				 * routine for ENOMEM, so drop the periph
+				 * lock to allow that recursion.
+				 */
+				if (error == ENOMEM)
+					cam_periph_unlock(periph);
 				biofinish(bp, NULL, error);
+				if (error == ENOMEM)
+					cam_periph_lock(periph);
 				xpt_release_ccb(start_ccb);
 				return;
 			}
diff --git a/sys/cam/nvme/nvme_da.c b/sys/cam/nvme/nvme_da.c
--- a/sys/cam/nvme/nvme_da.c
+++ b/sys/cam/nvme/nvme_da.c
@@ -1077,7 +1077,17 @@
 
 			trim = malloc(sizeof(*trim), M_NVMEDA, M_ZERO | M_NOWAIT);
 			if (trim == NULL) {
+				/*
+				 * We have to drop the periph lock when
+				 * returning ENOMEM. g_io_deliver treats these
+				 * request differently and will recursively call
+				 * the start routine which causes us to get into
+				 * ndastrategy with the periph lock held,
+				 * leading to a panic when its acquired again.
+				 */
+				cam_periph_unlock(periph);
 				biofinish(bp, NULL, ENOMEM);
+				cam_periph_lock(periph);
 				xpt_release_ccb(start_ccb);
 				ndaschedule(periph);
 				return;
diff --git a/sys/cam/scsi/scsi_da.c b/sys/cam/scsi/scsi_da.c
--- a/sys/cam/scsi/scsi_da.c
+++ b/sys/cam/scsi/scsi_da.c
@@ -3455,10 +3455,19 @@
 
 			queue_ccb = 0;
 
-			error = da_zone_cmd(periph, start_ccb, bp,&queue_ccb);
+			error = da_zone_cmd(periph, start_ccb, bp, &queue_ccb);
 			if ((error != 0)
 			 || (queue_ccb == 0)) {
+				/*
+				 * g_io_deliver will recurisvely call start
+				 * routine for ENOMEM, so drop the periph
+				 * lock to allow that recursion.
+				 */
+				if (error == ENOMEM)
+					cam_periph_unlock(periph);
 				biofinish(bp, NULL, error);
+				if (error == ENOMEM)
+					cam_periph_lock(periph);
 				xpt_release_ccb(start_ccb);
 				return;
 			}