diff --git a/sys/contrib/openzfs/module/os/freebsd/zfs/zfs_vfsops.c b/sys/contrib/openzfs/module/os/freebsd/zfs/zfs_vfsops.c
--- a/sys/contrib/openzfs/module/os/freebsd/zfs/zfs_vfsops.c
+++ b/sys/contrib/openzfs/module/os/freebsd/zfs/zfs_vfsops.c
@@ -1209,6 +1209,10 @@
 	vfsp->mnt_kern_flag |= MNTK_NO_IOPF;	/* vn_io_fault can be used */
 	vfsp->mnt_kern_flag |= MNTK_NOMSYNC;
 	vfsp->mnt_kern_flag |= MNTK_VMSETSIZE_BUG;
+	/*
+	 * We support copy_file_range() between multiple filesystems
+	 */
+	vfsp->mnt_kern_flag |= MNTK_COPYFR_MULTIFS;
 
 #if defined(_KERNEL) && !defined(KMEM_DEBUG)
 	vfsp->mnt_kern_flag |= MNTK_FPLOOKUP;
diff --git a/sys/contrib/openzfs/module/os/freebsd/zfs/zfs_vnops_os.c b/sys/contrib/openzfs/module/os/freebsd/zfs/zfs_vnops_os.c
--- a/sys/contrib/openzfs/module/os/freebsd/zfs/zfs_vnops_os.c
+++ b/sys/contrib/openzfs/module/os/freebsd/zfs/zfs_vnops_os.c
@@ -6241,6 +6241,13 @@
 	int error;
 	uint64_t len = *ap->a_lenp;
 
+	/* Make sure that both filesystems are ZFS */
+	if ((strcmp(invp->v_mount->mnt_vfc->vfc_name, "zfs") != 0) || (strcmp(
+	    outvp->v_mount->mnt_vfc->vfc_name, "zfs") != 0)) {
+		mp = NULL;
+		goto bad_write_fallback;
+	}
+
 	if (!zfs_bclone_enabled) {
 		mp = NULL;
 		goto bad_write_fallback;
diff --git a/sys/kern/vfs_vnops.c b/sys/kern/vfs_vnops.c
--- a/sys/kern/vfs_vnops.c
+++ b/sys/kern/vfs_vnops.c
@@ -3076,12 +3076,15 @@
 		goto out;
 
 	/*
-	 * If the two vnode are for the same file system, call
+	 * If the two vnode are for the same file system or both filesystems
+	 * support copy_file_range() between multiple filesystems, call
 	 * VOP_COPY_FILE_RANGE(), otherwise call vn_generic_copy_file_range()
 	 * which can handle copies across multiple file systems.
 	 */
 	*lenp = len;
-	if (invp->v_mount == outvp->v_mount)
+	if ((invp->v_mount == outvp->v_mount) ||
+	    (((invp->v_mount->mnt_kern_flag & MNTK_COPYFR_MULTIFS) != 0) &&
+	    ((outvp->v_mount->mnt_kern_flag & MNTK_COPYFR_MULTIFS) != 0)))
 		error = VOP_COPY_FILE_RANGE(invp, inoffp, outvp, outoffp,
 		    lenp, flags, incred, outcred, fsize_td);
 	else
diff --git a/sys/sys/mount.h b/sys/sys/mount.h
--- a/sys/sys/mount.h
+++ b/sys/sys/mount.h
@@ -493,6 +493,7 @@
 #define	MNTK_UNLOCKED_INSMNTQUE	0x00001000 /* fs does not lock the vnode for insmntque */
 #define	MNTK_UNMAPPED_BUFS	0x00002000
 #define	MNTK_USES_BCACHE	0x00004000 /* FS uses the buffer cache. */
+#define MNTK_COPYFR_MULTIFS	0x00008000 /* FS accepts copy_file_range() between multiple fileystems */
 /* UNUSED			0x00008000 */
 #define	MNTK_VMSETSIZE_BUG	0x00010000
 #define	MNTK_UNIONFS	0x00020000	/* A hack for F_ISUNIONSTACK */