diff --git a/crypto/openssl/ssl/tls13_enc.c b/crypto/openssl/ssl/tls13_enc.c
--- a/crypto/openssl/ssl/tls13_enc.c
+++ b/crypto/openssl/ssl/tls13_enc.c
@@ -471,6 +471,7 @@
     const EVP_CIPHER *cipher = NULL;
 #if !defined(OPENSSL_NO_KTLS) && defined(OPENSSL_KTLS_TLS13)
     ktls_crypto_info_t crypto_info;
+    void *rl_sequence;
     BIO *bio;
 #endif
 
@@ -724,8 +725,7 @@
         s->statem.enc_write_state = ENC_WRITE_STATE_VALID;
 #ifndef OPENSSL_NO_KTLS
 # if defined(OPENSSL_KTLS_TLS13)
-    if (!(which & SSL3_CC_WRITE)
-            || !(which & SSL3_CC_APPLICATION)
+    if (!(which & SSL3_CC_APPLICATION)
             || (s->options & SSL_OP_ENABLE_KTLS) == 0)
         goto skip_ktls;
 
@@ -741,7 +741,10 @@
     if (!ktls_check_supported_cipher(s, cipher, ciph_ctx))
         goto skip_ktls;
 
-    bio = s->wbio;
+    if (which & SSL3_CC_WRITE)
+        bio = s->wbio;
+    else
+        bio = s->rbio;
 
     if (!ossl_assert(bio != NULL)) {
         SSLfatal(s, SSL_AD_INTERNAL_ERROR, SSL_F_TLS13_CHANGE_CIPHER_STATE,
@@ -750,19 +753,26 @@
     }
 
     /* All future data will get encrypted by ktls. Flush the BIO or skip ktls */
-    if (BIO_flush(bio) <= 0)
-        goto skip_ktls;
+    if (which & SSL3_CC_WRITE) {
+        if (BIO_flush(bio) <= 0)
+            goto skip_ktls;
+    }
 
     /* configure kernel crypto structure */
-    if (!ktls_configure_crypto(s, cipher, ciph_ctx,
-                               RECORD_LAYER_get_write_sequence(&s->rlayer),
-                               &crypto_info, which & SSL3_CC_WRITE, iv, key,
-                               NULL, 0))
+    if (which & SSL3_CC_WRITE)
+        rl_sequence = RECORD_LAYER_get_write_sequence(&s->rlayer);
+    else
+        rl_sequence = RECORD_LAYER_get_read_sequence(&s->rlayer);
+
+    if (!ktls_configure_crypto(s, cipher, ciph_ctx, rl_sequence, &crypto_info,
+                               which & SSL3_CC_WRITE, iv, key, NULL, 0))
         goto skip_ktls;
 
     /* ktls works with user provided buffers directly */
-    if (BIO_set_ktls(bio, &crypto_info, which & SSL3_CC_WRITE))
-        ssl3_release_write_buffer(s);
+    if (BIO_set_ktls(bio, &crypto_info, which & SSL3_CC_WRITE)) {
+        if (which & SSL3_CC_WRITE)
+            ssl3_release_write_buffer(s);
+    }
 skip_ktls:
 # endif
 #endif