diff --git a/lib/libc/stdlib/Makefile.inc b/lib/libc/stdlib/Makefile.inc
--- a/lib/libc/stdlib/Makefile.inc
+++ b/lib/libc/stdlib/Makefile.inc
@@ -18,6 +18,8 @@
 	strtol.c strtold.c strtoll.c strtoq.c strtoul.c strtonum.c strtoull.c \
 	strtoumax.c strtouq.c system.c tdelete.c tfind.c tsearch.c twalk.c
 
+CFLAGS.qsort.c+= -Wsign-compare
+
 # Work around an issue on case-insensitive file systems.
 # libc has both _Exit.c and _exit.s and they both yield
 # _exit.o (case insensitively speaking).
diff --git a/lib/libc/stdlib/qsort.c b/lib/libc/stdlib/qsort.c
--- a/lib/libc/stdlib/qsort.c
+++ b/lib/libc/stdlib/qsort.c
@@ -171,7 +171,12 @@
 	pn = (char *)a + n * es;
 	d1 = MIN(pa - (char *)a, pb - pa);
 	vecswap(a, pb - d1, d1);
-	d1 = MIN(pd - pc, pn - pd - es);
+	/*
+	 * Cast es to preserve signedness of right-hand side of MIN()
+	 * expression, to avoid sign ambiguity in the implied comparison.  es
+	 * is safely within [0, SSIZE_MAX].
+	 */
+	d1 = MIN(pd - pc, pn - pd - (ssize_t)es);
 	vecswap(pb, pn - d1, d1);
 
 	d1 = pb - pa;