Index: sys/kern/uipc_domain.c
===================================================================
--- sys/kern/uipc_domain.c
+++ sys/kern/uipc_domain.c
@@ -175,6 +175,8 @@
 
 	if ((dp->dom_flags & DOMF_SUPPORTED) == 0)
 		return;
+	KASSERT((dp->dom_flags & DOMF_INITED) == 0 || !IS_DEFAULT_VNET(curvnet),
+	    ("Premature initialization of domain in non-default vnet"));
 	if (dp->dom_init)
 		(*dp->dom_init)();
 	for (pr = dp->dom_protosw; pr < dp->dom_protoswNPROTOSW; pr++)
@@ -186,6 +188,11 @@
 	max_datalen = MHLEN - max_hdr;
 	if (max_datalen < 1)
 		panic("%s: max_datalen < 1", __func__);
+	if (IS_DEFAULT_VNET(curvnet)) {
+		KASSERT((dp->dom_flags & DOMF_INITED) == 0,
+		    ("Double init of domain"));
+		dp->dom_flags |= DOMF_INITED;
+	}
 }
 
 #ifdef VIMAGE
@@ -234,15 +241,6 @@
 	if (domain_init_status < 1)
 		printf("WARNING: attempt to domain_add(%s) before "
 		    "domaininit()\n", dp->dom_name);
-#endif
-#ifdef notyet
-	KASSERT(domain_init_status < 2,
-	    ("attempt to domain_add(%s) after domainfinalize()",
-	    dp->dom_name));
-#else
-	if (domain_init_status >= 2)
-		printf("WARNING: attempt to domain_add(%s) after "
-		    "domainfinalize()\n", dp->dom_name);
 #endif
 	mtx_unlock(&dom_mtx);
 }
@@ -489,10 +487,13 @@
 	struct protosw *pr;
 
 	NET_EPOCH_ENTER(et);
-	for (dp = domains; dp; dp = dp->dom_next)
+	for (dp = domains; dp; dp = dp->dom_next) {
+		if ((dp->dom_flags & DOMF_INITED) == 0)
+			continue;
 		for (pr = dp->dom_protosw; pr < dp->dom_protoswNPROTOSW; pr++)
 			if (pr->pr_slowtimo)
 				(*pr->pr_slowtimo)();
+	}
 	NET_EPOCH_EXIT(et);
 	callout_reset(&pfslow_callout, hz/2, pfslowtimo, NULL);
 }
@@ -505,10 +506,13 @@
 	struct protosw *pr;
 
 	NET_EPOCH_ENTER(et);
-	for (dp = domains; dp; dp = dp->dom_next)
+	for (dp = domains; dp; dp = dp->dom_next) {
+		if ((dp->dom_flags & DOMF_INITED) == 0)
+			continue;
 		for (pr = dp->dom_protosw; pr < dp->dom_protoswNPROTOSW; pr++)
 			if (pr->pr_fasttimo)
 				(*pr->pr_fasttimo)();
+	}
 	NET_EPOCH_EXIT(et);
 	callout_reset(&pffast_callout, hz/5, pffasttimo, NULL);
 }
Index: sys/sys/domain.h
===================================================================
--- sys/sys/domain.h
+++ sys/sys/domain.h
@@ -73,6 +73,7 @@
 
 /* dom_flags */
 #define	DOMF_SUPPORTED	0x0001	/* System supports this domain. */
+#define	DOMF_INITED	0x0002	/* Initialized in the default vnet. */
 
 #ifdef _KERNEL
 extern int	domain_init_status;