Index: head/biology/Makefile
===================================================================
--- head/biology/Makefile
+++ head/biology/Makefile
@@ -88,6 +88,7 @@
     SUBDIR += py-biopython
     SUBDIR += py-bx-python
     SUBDIR += py-cutadapt
+    SUBDIR += py-macs2
     SUBDIR += py-pysam
     SUBDIR += pycogent
     SUBDIR += pyfasta
Index: head/biology/py-macs2/Makefile
===================================================================
--- head/biology/py-macs2/Makefile
+++ head/biology/py-macs2/Makefile
@@ -0,0 +1,31 @@
+# $FreeBSD$
+
+PORTNAME=	macs2
+PORTVERSION=	2.1.0.p20170505
+CATEGORIES=	biology python
+PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
+
+MAINTAINER=	jwb@FreeBSD.org
+COMMENT=	Analysis of chromatin immunoprecipitation (ChIP) sequences
+
+LICENSE=	BSD3CLAUSE
+LICENSE_FILE=	${WRKSRC}/COPYING
+
+BUILD_DEPENDS=	${PYTHON_PKGNAMEPREFIX}numpy>0:math/py-numpy@${PY_FLAVOR}
+
+USES=		python
+USE_PYTHON=	autoplist concurrent cython distutils
+
+USE_GITHUB=	yes
+GH_ACCOUNT=	taoliu
+GH_PROJECT=	MACS
+GH_TAGNAME=	6946b2f
+
+PYSETUP=	setup_w_cython.py
+
+post-stage:
+	${STRIP_CMD} \
+		${STAGEDIR}${PYTHON_SITELIBDIR}/MACS2/*.so \
+		${STAGEDIR}${PYTHON_SITELIBDIR}/MACS2/*/*.so
+
+.include <bsd.port.mk>
Index: head/biology/py-macs2/distinfo
===================================================================
--- head/biology/py-macs2/distinfo
+++ head/biology/py-macs2/distinfo
@@ -0,0 +1,3 @@
+TIMESTAMP = 1512241922
+SHA256 (taoliu-MACS-2.1.0.p20170505-6946b2f_GH0.tar.gz) = c6e4fb8b69b955134399fcdfc075cea5fbc29fabbc46cc4e9acdedeb1174fcfd
+SIZE (taoliu-MACS-2.1.0.p20170505-6946b2f_GH0.tar.gz) = 159560613
Index: head/biology/py-macs2/pkg-descr
===================================================================
--- head/biology/py-macs2/pkg-descr
+++ head/biology/py-macs2/pkg-descr
@@ -0,0 +1,6 @@
+MACS is a tool for chromatin immunoprecipitation (ChIP) sequence analysis.
+MACS empirically models the length of the sequenced ChIP fragments, which
+tend to be shorter than sonication or library construction size estimates,
+and uses it to improve the spatial resolution of predicted binding sites.
+
+WWW: https://github.com/taoliu/MACS