diff --git a/sys/cam/ctl/ctl.c b/sys/cam/ctl/ctl.c
--- a/sys/cam/ctl/ctl.c
+++ b/sys/cam/ctl/ctl.c
@@ -4923,8 +4923,7 @@
 	int retval;
 
 	CTL_DEBUG_PRINT(("ctl_config_move_done\n"));
-	KASSERT(io->io_hdr.io_type == CTL_IO_SCSI,
-	    ("%s: unexpected I/O type %x", __func__, io->io_hdr.io_type));
+	CTL_IO_ASSERT(io, SCSI);
 
 	if (ctl_debug & CTL_DEBUG_CDB_DATA)
 		ctl_data_print(io);
@@ -10560,8 +10559,7 @@
 ctl_get_lba_len(union ctl_io *io, uint64_t *lba, uint64_t *len)
 {
 
-	KASSERT(io->io_hdr.io_type == CTL_IO_SCSI,
-	    ("%s: unexpected I/O type %x", __func__, io->io_hdr.io_type));
+	CTL_IO_ASSERT(io, SCSI);
 
 	switch (io->scsiio.cdb[0]) {
 	case COMPARE_AND_WRITE: {
@@ -10741,8 +10739,7 @@
 	uint64_t lba;
 	uint32_t len;
 
-	KASSERT(io->io_hdr.io_type == CTL_IO_SCSI,
-	    ("%s: unexpected I/O type %x", __func__, io->io_hdr.io_type));
+	CTL_IO_ASSERT(io, SCSI);
 
 	/* If not UNMAP -- go other way. */
 	if (io->scsiio.cdb[0] != UNMAP)
@@ -12323,8 +12320,7 @@
 	struct bintime cur_bt;
 #endif
 
-	KASSERT(io->io_hdr.io_type == CTL_IO_SCSI,
-	    ("%s: unexpected I/O type %x", __func__, io->io_hdr.io_type));
+	CTL_IO_ASSERT(io, SCSI);
 
 #ifdef CTL_TIME_IO
 	getbinuptime(&cur_bt);
diff --git a/sys/cam/ctl/ctl_backend_block.c b/sys/cam/ctl/ctl_backend_block.c
--- a/sys/cam/ctl/ctl_backend_block.c
+++ b/sys/cam/ctl/ctl_backend_block.c
@@ -1819,8 +1819,7 @@
 
 	be_lun = (struct ctl_be_block_lun *)CTL_BACKEND_LUN(io);
 
-	KASSERT(io->io_hdr.io_type == CTL_IO_SCSI,
-	    ("%s: unexpected I/O type %x", __func__, io->io_hdr.io_type));
+	CTL_IO_ASSERT(io, SCSI);
 
 	PRIV(io)->len = 0;
 
diff --git a/sys/cam/ctl/ctl_io.h b/sys/cam/ctl/ctl_io.h
--- a/sys/cam/ctl/ctl_io.h
+++ b/sys/cam/ctl/ctl_io.h
@@ -592,6 +592,21 @@
 };
 
 #ifdef _KERNEL
+#define	_CTL_IO_ASSERT_1(io, _1)					\
+	KASSERT((io)->io_hdr.io_type == CTL_IO_##_1,			\
+	    ("%s: unexpected I/O type %x", __func__, (io)->io_hdr.io_type))
+
+#define	_CTL_IO_ASSERT_2(io, _1, _2)					\
+	KASSERT((io)->io_hdr.io_type == CTL_IO_##_1 ||			\
+	    (io)->io_hdr.io_type == CTL_IO_##_2,			\
+	    ("%s: unexpected I/O type %x", __func__, (io)->io_hdr.io_type))
+
+#define	_CTL_IO_ASSERT_MACRO(io, _1, _2, NAME, ...)			\
+	NAME
+
+#define	CTL_IO_ASSERT(...)						\
+	_CTL_IO_ASSERT_MACRO(__VA_ARGS__, _CTL_IO_ASSERT_2,		\
+	    _CTL_IO_ASSERT_1)(__VA_ARGS__)
 
 union ctl_io *ctl_alloc_io(void *pool_ref);
 union ctl_io *ctl_alloc_io_nowait(void *pool_ref);
diff --git a/sys/cam/ctl/scsi_ctl.c b/sys/cam/ctl/scsi_ctl.c
--- a/sys/cam/ctl/scsi_ctl.c
+++ b/sys/cam/ctl/scsi_ctl.c
@@ -1908,8 +1908,7 @@
 	struct cam_periph *periph;
 	struct ctlfe_lun_softc *softc;
 
-	KASSERT(io->io_hdr.io_type == CTL_IO_SCSI,
-	    ("%s: unexpected I/O type %x", __func__, io->io_hdr.io_type));
+	CTL_IO_ASSERT(io, SCSI);
 
 	io->scsiio.ext_data_filled = 0;
 	ccb = PRIV_CCB(io);