diff --git a/Mk/Uses/cargo.mk b/Mk/Uses/cargo.mk
--- a/Mk/Uses/cargo.mk
+++ b/Mk/Uses/cargo.mk
@@ -194,7 +194,7 @@
 CARGO_TEST_ARGS+=	--features='${CARGO_FEATURES:N--no-default-features}'
 .  endif
 
-.  if !defined(WITH_DEBUG)
+.  if !defined(_WITH_DEBUG)
 CARGO_BUILD_ARGS+=	--release
 CARGO_TEST_ARGS+=	--release
 .  else
diff --git a/Mk/Uses/cmake.mk b/Mk/Uses/cmake.mk
--- a/Mk/Uses/cmake.mk
+++ b/Mk/Uses/cmake.mk
@@ -83,13 +83,13 @@
 RUN_DEPENDS+=		${CMAKE_BIN}:devel/cmake-core
 .    endif
 
-.    if defined(WITH_DEBUG)
+.    if defined(_WITH_DEBUG)
 CMAKE_BUILD_TYPE?=	Debug
-.    elif defined(WITH_DEBUGINFO)
+.    elif defined(_WITH_DEBUGINFO)
 CMAKE_BUILD_TYPE?=	RelWithDebInfo
 .    else
 CMAKE_BUILD_TYPE?=	Release
-.    endif #defined(WITH_DEBUG)
+.    endif #defined(_WITH_DEBUG)
 
 CMAKE_ARGS+=		-DCMAKE_C_COMPILER:STRING="${CC}" \
 			-DCMAKE_CXX_COMPILER:STRING="${CXX}" \
@@ -128,7 +128,7 @@
 .  endif
 
 .  if empty(cmake_ARGS:Mindirect)
-.    if defined(STRIP) && ${STRIP} != "" && !defined(WITH_DEBUG) && !defined(WITH_DEBUGINFO)
+.    if defined(STRIP) && ${STRIP} != "" && !defined(_WITH_DEBUG) && !defined(_WITH_DEBUGINFO)
 INSTALL_TARGET?=	install/strip
 .    endif
 .  endif
diff --git a/Mk/Uses/go.mk b/Mk/Uses/go.mk
--- a/Mk/Uses/go.mk
+++ b/Mk/Uses/go.mk
@@ -90,13 +90,13 @@
 GO_TARGET?=	${GO_PKGNAME}
 GO_TESTTARGET?=	./...
 
-.  if !defined(PIE_UNSAFE) && defined(WITH_PIE) && ${ARCH} == amd64
+.  if !defined(PIE_UNSAFE) && defined(_WITH_PIE) && ${ARCH} == amd64
 GO_BUILDFLAGS+= -buildmode=pie
 .  else
 GO_BUILDFLAGS+= -buildmode=exe
 .  endif
 GO_BUILDFLAGS+= -v -trimpath
-.  if !defined(WITH_DEBUG) && empty(GO_BUILDFLAGS:M-ldflags*)
+.  if !defined(_WITH_DEBUG) && empty(GO_BUILDFLAGS:M-ldflags*)
 GO_BUILDFLAGS+=	-ldflags=-s
 .  endif
 GO_TESTFLAGS+=	-v
diff --git a/Mk/Uses/grantlee.mk b/Mk/Uses/grantlee.mk
--- a/Mk/Uses/grantlee.mk
+++ b/Mk/Uses/grantlee.mk
@@ -65,7 +65,7 @@
 # GrantleeMacros.cmake provides grantlee_adjust_plugin_name() which appends a
 # letter 'd' to the library name in Debug mode. Provide a PLIST_SUB which can be
 # appended in the plist.
-.  if defined(WITH_DEBUG)
+.  if defined(_WITH_DEBUG)
 PLIST_SUB+=	GRANTLEE_DEBUG_SUFFIX=d
 .  else
 PLIST_SUB+=	GRANTLEE_DEBUG_SUFFIX=""
diff --git a/Mk/Uses/meson.mk b/Mk/Uses/meson.mk
--- a/Mk/Uses/meson.mk
+++ b/Mk/Uses/meson.mk
@@ -51,9 +51,9 @@
 INSTALL_TARGET=		install
 
 # should we have strip separate from WITH_DEBUG?
-.  if defined(WITH_DEBUG)
+.  if defined(_WITH_DEBUG)
 CONFIGURE_ARGS+=	--buildtype debug
-.  elif defined(WITH_DEBUGINFO)
+.  elif defined(_WITH_DEBUGINFO)
 CONFIGURE_ARGS+=	--buildtype debugoptimized
 .  else
 CONFIGURE_ARGS+=	--buildtype release \
diff --git a/Mk/Uses/php.mk b/Mk/Uses/php.mk
--- a/Mk/Uses/php.mk
+++ b/Mk/Uses/php.mk
@@ -208,7 +208,7 @@
 PHP_EXT_DIR:=	${PHP_EXT_DIR}-zts
 .    endif
 
-.    if defined(WITH_DEBUG)
+.    if defined(_WITH_DEBUG)
 PHP_EXT_DIR:=	${PHP_EXT_DIR}-debug
 .    endif
 PHP_SAPI?=	""
diff --git a/Mk/Uses/qmake.mk b/Mk/Uses/qmake.mk
--- a/Mk/Uses/qmake.mk
+++ b/Mk/Uses/qmake.mk
@@ -16,7 +16,7 @@
 # norecursive		Don't pass -recursive argument to qmake binary
 # outsource		Perform an out-of-source build
 # no_env		Suppress modification of configure and make environment.
-# no_configure		Don't add the configure target -- this is implied by 
+# no_configure		Don't add the configure target -- this is implied by
 #			HAS_CONFIGURE=yes and GNU_CONFIGURE=yes
 #
 #
@@ -75,7 +75,7 @@
 			QMAKE_CXXFLAGS_RELEASE="" \
 			PREFIX="${PREFIX}"
 
-.  if defined(WITH_DEBUG)
+.  if defined(_WITH_DEBUG)
 PLIST_SUB+=		DEBUG=""
 QMAKE_ARGS+=		CONFIG+="debug separate_debug_info" \
 			CONFIG-="release"
@@ -83,7 +83,7 @@
 PLIST_SUB+=		DEBUG="@comment "
 QMAKE_ARGS+=		CONFIG+="release" \
 			CONFIG-="debug separate_debug_info"
-.  endif # defined(WITH_DEBUG)
+.  endif # defined(_WITH_DEBUG)
 
 # We set -recursive by default to keep qmake from running in the build stage.
 .  if ! ${qmake_ARGS:Mnorecursive}
diff --git a/Mk/Uses/qt-dist.mk b/Mk/Uses/qt-dist.mk
--- a/Mk/Uses/qt-dist.mk
+++ b/Mk/Uses/qt-dist.mk
@@ -239,7 +239,7 @@
 CONFIGURE_ARGS+=	-recheck-all
 .  endif # ${_QT_VER:M5}
 
-.  if defined(WANT_QT_DEBUG) || defined(WITH_DEBUG)
+.  if defined(WANT_QT_DEBUG) || defined(_WITH_DEBUG)
 WITH_DEBUG=		yes
 STRIP=			# It's done prior to bsd.qt.mk inclusion.
 CONFIGURE_ARGS+=	-debug -separate-debug-info
@@ -250,7 +250,7 @@
 CONFIGURE_ARGS+=	-release -no-separate-debug-info
 QMAKE_ARGS+=		QT_CONFIG+="release" \
 			QT_CONFIG-="debug separate_debug_info"
-.  endif # defined(WANT_QT_DEBUG) || defined(WITH_DEBUG)
+.  endif # defined(WANT_QT_DEBUG) || defined(_WITH_DEBUG)
 
 .  if defined(WANT_QT_VERBOSE_CONFIGURE)
 CONFIGURE_ARGS+=	-verbose
@@ -302,7 +302,7 @@
 
 PLIST_SUB+=		SHORTVER=${_QT_VERSION:R} \
 			FULLVER=${_QT_VERSION:C/-.*//}
-.  if defined(WITH_DEBUG)
+.  if defined(_WITH_DEBUG)
 PLIST_SUB+=		DEBUG="" \
 			NO_DEBUG="@comment "
 .  else